|
|
5-formyltetrahydrofolate + ATP <=> 5,10-methenyltetrahydrofolate + ADP + phosphate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
MK
|
|
BRENDA:
BR127;
BS453763
KEGG:
R02301
MetaCyc:
5-FORMYL-THF-CYCLO-LIGASE-RXN
SABIO-RK:
2263
|
|
|
|
5,10-methenyltetrahydrofolate + H2O <=> 5-formyltetrahydrofolate + H+
|
2.1.2.10
aminomethyltransferase
3.5.4.9
methenyltetrahydrofolate cyclohydrolase
|
–
–
|
MK
|
|
BRENDA:
BS372118
KEGG:
R02300
MetaCyc:
RXN-6321
SABIO-RK:
2262
|
|
|
|
5-formyltetrahydrofolate + L-glutamate <=> N-formyl-L-glutamate + tetrahydrofolate + H+
|
2.1.2.5
glutamate formimidoyltransferase
|
–
|
K
|
|
BRENDA:
BS320077
KEGG:
R03189
MetaCyc:
RXN-20716
|
|
|
|
5-formyltetrahydrofolate + H2O <=> 5-formylpteroate + L-glutamate
|
3.4.17.11
glutamate carboxypeptidase
|
–
|
|
|
BRENDA:
BS361736
SABIO-RK:
12932
|
|
|
|
tRNA_containing_2-thiouridine + glycine + 5-formyltetrahydrofolate + reduced_acceptor <=> tRNA_containing_5-carboxymethylaminomethyl-2-thiouridine + tetrahydrofolate + acceptor + H2O
|
not assigned
|
–
|
|
|
KEGG:
R08701
|
|
|
|
5-formyltetrahydrofolate + L-glutamate + ATP <=> 5-formyltetrahydrofolate + ADP + phosphate
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
|
|
MetaCyc:
RXN-6341
|
|
|
|
ATPgammaS + 5-formyltetrahydrofolate <=> ADPbetaS + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS646
|
|
|
|
ara-ATP + 5-formyltetrahydrofolate <=> araADP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS645
|
|
|
|
dATP + 5-formyltetrahydrofolate <=> dADP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS643
|
|
|
|
dTTP + 5-formyltetrahydrofolate <=> dTDP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS644
|
|
|
|
ITP + 5-formyltetrahydrofolate <=> IDP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS642
|
|
|
|
GTP + 5-formyltetrahydrofolate <=> GDP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS641
|
|
|
|
5-formyltetrahydrofolate_glutamate + H2O <=> 5-formyltetrahydrofolate + L-glutamate
|
3.4.19.9
folate gamma-glutamyl hydrolase
|
–
|
|
|
BRENDA:
BS431425
|
|
|
|
5-formyltetrahydrofolate_heptaglutamate + 7 H2O <=> 5-formyltetrahydrofolate + 7 L-glutamate
|
3.4.19.9
folate gamma-glutamyl hydrolase
|
–
|
|
|
BRENDA:
BS431426
|
|
|
|
5-formyltetrahydrofolate_hexaglutamate + 6 H2O <=> 5-formyltetrahydrofolate + 6 L-glutamate
|
3.4.19.9
folate gamma-glutamyl hydrolase
|
–
|
|
|
BRENDA:
BS431427
|
|
|
|
10-formyltetrahydrofolate <=> 5-formyltetrahydrofolate + H2O
|
3.5.4.9
methenyltetrahydrofolate cyclohydrolase
|
–
|
|
|
BRENDA:
BS371530
|
|
|
|
CTP + 5-formyltetrahydrofolate <=> CDP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS639
|
|
|
|
CTP + 5-formyltetrahydrofolate <=> CDP + phosphate + 5,10-methenyltetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS453764
|
|
|
|
UTP + 5-formyltetrahydrofolate <=> UDP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS640
|
|
|
|
UTP + 5-formyltetrahydrofolate <=> UDP + phosphate + 5,10-methenyltetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
|
|
BRENDA:
BS453765
|
|
|
|
ATP + 5-formyltetrahydrofolate + L-glutamate <=> ADP + 5-formyl-5,6,7,8-tetrahydropteroyl-Glu2 + phosphate
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
|
|
BRENDA:
BS369053
|
|
|
|
ATP + 5-formyltetrahydrofolate <=> ADP + phosphate + 5,10-methylenetetrahydrofolate
|
6.3.3.2
5-formyltetrahydrofolate cyclo-ligase
|
–
|
B
|
|
BRENDA:
BS638
|
|
|
|
ATP + 5-formyltetrahydrofolate + L-glutamate <=> ADP + phosphate + (6S)-5-formyl-5,6,7,8-tetrahydropteroyl-Glu2
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
|
|
BRENDA:
BS369048
|
|